Organism C. immitis

Coccidioidomycosis (spherule)

Coccidioidomycosis (KOH) rupturing mature spherule

Coccidioidomycosis (arthroconidia from colony)

Lung Infection

Lung: large spherule on right side of image

Lung (chronic)

Lung (hematoxylin-eosin stain)

Lung (hematoxylin-eosin stain)

Lung (hematoxylin-eosin stain)

Lung (hematoxylin-eosin stain)

Lung spherule (PAS stain)

Lung (Gomori's silver) hyphal elements and spherules

Lung (Gomori's silver)

Lung (Gomori's silver) spherules & endospores

Lung (Gomori's silver) hyphal elements & spherules

Lung (silver methenamine) spherules

Lung, hyphal form, Gomori, spherules

Skin Involvement

Skin (PAS)

Skin (PAS)

Skin & accessories

Skin (Gomori's silver)

Brain Involvement

Brain, large maturing spherules

Meningitis, cerebral membranes

Brain, basilar meningitis, gross dissection